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Testosterone-Induced Water Retention

A study looking at various doses of testosterone enanthate in older men revealed nearly half experienced leg edema in the groups provided with supraphysiologic testosterone (300 and 600 milligrams per week of testosterone enanthate).2 Sodium and potassium are usually maintained in a balanced range through the actions of a multitude of hormones and chemokines that act primarily on the kidneys. Obviously, adequate water consumption plays a role as well, maintained by other hormones that stimulate thirst.

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